https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54333 1.8. The primary outcome was good functional outcome at 90 days, defined as a modified Rankin Scale (mRS) score 0-2. follow-up infarct volume, core expansion and penumbral salvage volumes were secondary outcomes. Of 572 anterior circulation EVT patients, CTP source image data required to generate objective maps were available in 170, and a Target Mismatch was present in 151 (89%). The rate of 90-day good functional outcome was similar between Target Mismatch (53%) and Large Core Non-Mismatch groups (46%, p = 0.629). Median follow-up infarct volume in the Large Core Non-Mismatch group (104ml [IQR 25ml-189ml]) was larger than that in the Target Mismatch patients (16ml [8ml-47ml], p<0.001). Despite a lack of formal CTP selection criteria, the majority of patients treated at our centres had a Target Mismatch. Patients without Target Mismatch had larger follow-up infarct volumes, but the functional recovery rate was similar to that in Target Mismatch patients. Infarct volumes should be included as objective assessment criteria in the evaluation of the efficacy of EVT in non-Target Mismatch patients.]]> Tue 20 Feb 2024 16:05:37 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35875 Tue 17 Dec 2019 14:15:42 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41993 6 s (sensitivity, 88%; specificity, 92%). The computed tomographic perfusion collateral index, defined by the ratio of delay time >6 s/delay time >2 s volume, showed a significant correlation with dynamic computed tomographic angiography collateral scores (correlation coefficient, 0.62; P<0.001), with an optimal cut point of 31.8% in predicting good collateral status (sensitivity of 83% and specificity of 86%). When predicting good clinical outcome, the delay time collateral index showed a similar predictive power to dynamic computed tomographic angiography collaterals (area under the curve, 0.78 [0.67–0.83] and 0.77 [0.69–0.84], respectively; P<0.001). Conclusions—Computed tomographic perfusion can accurately quantify collateral flow after acute ischemic stroke.]]> Tue 16 Aug 2022 16:37:23 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37847 Thu 28 Oct 2021 12:36:07 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36439 Thu 27 Jan 2022 15:55:31 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19528 Sat 24 Mar 2018 08:02:04 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17440 Sat 24 Mar 2018 08:01:35 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:23459 Sat 24 Mar 2018 07:13:01 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46655 Mon 28 Nov 2022 17:43:31 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33119 Mon 27 Aug 2018 18:24:19 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48518 p < 0.001). Vessel occlusion location was not a strong predictor of outcomes compared to baseline ischemic core (area under the curve, mRS 0-1, 0.64 vs 0.83; mRS 0-2, 0.70 vs 0.86, p < 0.001). There was no interaction between occlusion location and ischemic core (interaction coefficient 1.00, p = 0.798). Conclusions: Ischemic stroke patients with a distal occlusion have higher rate of excellent and favorable outcome than patients with an M1 occlusion. The baseline ischemic core was shown to be a more powerful predictor of functional outcome than the occlusion location, but the relationship between ischemic core and outcome does not different by occlusion locations.]]> Mon 20 Mar 2023 17:06:46 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41051 p < 0.001). The relationship of core growth and CTP collateral index was validated in cohort 2. An increment in collateral index by 1% resulted in an increase of core growth by 0.59 mL/h (coefficient 0.59 [0.48–0.71], p < 0.001) in cohort 2. Conclusion: Collateral status is a major determinant of ischemic core growth.]]> Mon 08 Aug 2022 14:50:17 AEST ]]>